In The News

Casa Santo Stefano – Ybor’s New Sicilian Restaurant

The restaurant celebrates the Sicilian immigrant families who moved to Tampa in the early 1900s.

Read More →

What will a pandemic Valentine’s Day in Tampa Bay look like?

At Casa Santo Stefano in Ybor City guests can choose to dine in or opt for a Valentine’s Day dinner to-go.

Read More →

Sorry, we couldn't find any posts. Please try a different search.

Columbia Restaurant Group Launching New Sicilian Restaurant 

Casa Santo Stefano is set to be the next big thing in Tampa’s food scene.

Read More →

Columbia Restaurant Group Opening Casa Santo Stefano in Ybor City on Thursday, November 19

Intended to bring Sicilian flavor to the highly Italian populated city, the new restaurant will now honor that.

Read More →

Get Social With Us

Join Our Team

Apply Monday–Friday from 2–4 p.m. at Casa Santo Stefano, or send your resume to [email protected].

Lunch: 11 a.m to 4 p.m
Dinner: 4 p.m to 10 p.m

Santo’s Drinkeria:
Sunday – Thursday: 5 to 10 p.m.
Friday & Saturday: 5 to 11 p.m.