We’re Proud to Serve South Tampa, FL

Casa Santo Stefano is proud to have curated a delicious lunch menu, dinner menu, and Santo’s Drinkeria Menu to honor the Sicilian culture. Our menus feature authentic dishes, full-bodied wines and refreshing cocktails, including maccheroni (pasta), steaks, seafood, scacciata, salads, soups, desserts, and hundreds of Sicilian wines.

We are located at 1607 N. 22nd Street, Tampa, Florida 33605. Casa Santo Stefano is proud to serve the people of Ybor City and the surrounding communities of Palmetto Beach, Downtown TampaHyde Park, East Tampa, South TampaChannelside,  Davis Islands, and Bayshore.

Popular Attractions in South Tampa

Sylvan Ramble Lights

What started as a small computerized light show, has turned into one of the biggest holiday light shows in the area! Sylvan Ramble Lights takes Christmas lights a step further, including lights around Halloween and cool effects, like water and smoke.

Butterfly Conservatory of Tampa Bay
The Butterfly Conservatory hosts an educational exhibit in a tranquil, tropical oasis, filled with thousands of native and exotic free-flying butterflies. Enjoy an immersive, magical experience at the Butterfly Conservatory.
Fred Ball Park

Fred Ball Park is a small, dog-friendly green park, overlooking the bay with a gazebo and tennis court. Take in the beautiful scenery, right in the middle of Bayshore Boulevard, with a nice, quiet experience.

Come visit Casa Santo Stefano!

No matter where you choose to visit in Ybor City, you really can’t go wrong! We encourage you to come experience true Tampa Sicilian food at Casa Santo Stefano. At Casa, it’s not just a meal; it’s an experience.

Salute to Sunday suppers, simpler times, and shared stories at Casa Santo Stefano.

Experience the One-of-a-Kind Beauty in South Tampa, FL

We hope you love South Tampa just as much as we do. We are honored to serve the people in and around our communities.